BIOCEV parasitologists help develop more effective vaccines against poultry diseases
Projects — 28.11.2024

BIOPHARM

BIOCEV parasitologists help develop more effective vaccines against poultry diseases

Parasitologists from the Faculty of Science of Charles University in the BIOCEV centre are helping BIOPHARM, Research Institute of Biopharmaceutics and Veterinary Medicines to reveal the molecular basis of the pathogenicity of parasites of the genus Eimeria (specifically Eimeria tenella). These parasites (coccidia) cause the fatal poultry disease coccidiosis, the clinical outbreak of which has a significant impact on the food industry.

 

Currently, there is an effective vaccination that was developed by BIOPHARM, Research Institute of Biopharmaceutics and Veterinary Medicines and is based on the application of so-called attenuated lines that induce immunity against pathogens. The current joint research of the Faculty of Science and BIOPHARM, Research Institute of Biopharmaceutics and Veterinary Medicines, supported by the call for applications I of the Ministry of Trade and Industry, is aimed at discovering the molecular basis of why pathogenic coccidia cause disease and in which biological properties they differ from attenuated lines. This research will enable the development of diagnostics to differentiate pathogenic and attenuated lineages and serve to develop more effective vaccinations.

Eimeria tenella (source: Jan Tachezy)

Contact: Prof. Jan Tachezy

Title photo: freepik.com

Project "New methods in the development of poultry vaccines at BIOPHARM, Research Institute of Biopharmaceutics and Veterinary Medicines - Application I." is co-financed by the European Union. 

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